Rimegepant and Ciclosporin (Sandimmun Neoral 100 mg Yumuşak Jelatin Kapsül): interaction and safety
This source-based reference is not a personal treatment recommendation. The relevance and management of an interaction depend on the exact products, route, dose and clinical situation.
Interaction mechanism
Potent P-glycoprotein inhibition can increase rimegepant exposure.
Clinical significance and safety
Cyclosporine is among the potent P-glycoprotein inhibitors named in the rimegepant prescribing information. It may increase rimegepant exposure, and the label restricts how soon another rimegepant dose can be taken. The prescriber or pharmacist should review the schedule before these medicines are combined.
Using this information
This is a source-based reference record, not a recommendation to combine, stop or change medicines. A missing interaction record does not establish safe use. A qualified healthcare professional should consider the exact products, doses, other medicines and individual health circumstances.