Cipro (Ciprofloxacin) 500 mg (Cipro 500 mg) and Indomethacin: interaction and safety
This source-based reference is not a personal treatment recommendation. The relevance and management of an interaction depend on the exact products, route, dose and clinical situation.
Interaction mechanism
Systemic fluoroquinolone and NSAID co-treatment requires caution about CNS adverse effects and seizures.
Clinical significance and safety
Cipro (Ciprofloxacin) 500 mg and Indomethacin: Systemic fluoroquinolone and NSAID co-treatment requires caution about CNS adverse effects and seizures. The warning depends on the precise medicines and patient risk factors; it does not establish a seizure rate for this pair. A new seizure requires emergency assessment. Cancer, neurological or psychiatric treatment should not be changed without the treating team.
Using this information
This is a source-based reference record, not a recommendation to combine, stop or change medicines. A missing interaction record does not establish safe use. A qualified healthcare professional should consider the exact products, doses, other medicines and individual health circumstances.