Cipro (Ciprofloxacin) 500 mg (Cipro 500 mg) and Ziprasidone: interaction and safety
This source-based reference is not a personal treatment recommendation. The relevance and management of an interaction depend on the exact products, route, dose and clinical situation.
Interaction mechanism
Ciprofloxacin and ziprasidone have overlapping QT effects that can increase serious cardiac risk.
Clinical significance and safety
Cipro (Ciprofloxacin) 500 mg and Ziprasidone: Ciprofloxacin and ziprasidone have overlapping QT effects that can increase serious cardiac risk. The ziprasidone label advises avoiding other established QT-prolonging drugs. Heart disease, a slow pulse and low potassium or magnesium can increase concern. A clinician determines whether ECG or electrolyte checks are needed. Fainting or new irregular palpitations require urgent assessment.
Using this information
This is a source-based reference record, not a recommendation to combine, stop or change medicines. A missing interaction record does not establish safe use. A qualified healthcare professional should consider the exact products, doses, other medicines and individual health circumstances.