Prednisolone (Deltacortril 5 mg Tablet) and Upadacitinib: interaction and safety
This source-based reference is not a personal treatment recommendation. The relevance and management of an interaction depend on the exact products, route, dose and clinical situation.
Interaction mechanism
Concomitant systemic corticosteroids are a flagged factor for gastrointestinal-perforation monitoring.
Clinical significance and safety
Deltacortril 5 mg Tablet contains a systemic corticosteroid. Upadacitinib labeling calls for monitoring in patients at risk of gastrointestinal perforation, including those using corticosteroids; this does not mean all such combinations are automatically contraindicated. New abdominal pain or infection symptoms should be reviewed promptly by the treating team.
Using this information
This is a source-based reference record, not a recommendation to combine, stop or change medicines. A missing interaction record does not establish safe use. A qualified healthcare professional should consider the exact products, doses, other medicines and individual health circumstances.