Fluconazole (Flucoral 150 mg) and Rimegepant: interaction and safety
This source-based reference is not a personal treatment recommendation. The relevance and management of an interaction depend on the exact products, route, dose and clinical situation.
Interaction mechanism
Moderate CYP3A4 inhibition can increase rimegepant exposure.
Clinical significance and safety
Fluconazole can increase rimegepant exposure through moderate CYP3A4 inhibition. The rimegepant label requires a longer interval before another rimegepant dose; the prescriber or pharmacist should check the exact regimen rather than the patient changing it independently.
Using this information
This is a source-based reference record, not a recommendation to combine, stop or change medicines. A missing interaction record does not establish safe use. A qualified healthcare professional should consider the exact products, doses, other medicines and individual health circumstances.