Verapamil hydrochloride (İsoptin 120 mg) and Voclosporin: interaction and safety
This source-based reference is not a personal treatment recommendation. The relevance and management of an interaction depend on the exact products, route, dose and clinical situation.
Interaction mechanism
Moderate CYP3A4 inhibition increases voclosporin exposure.
Clinical significance and safety
İsoptin 120 mg contains a moderate CYP3A4 inhibitor named in the voclosporin label. The combination requires a prescriber-directed modification and monitoring, particularly of kidney function and adverse effects. This page does not supply a dose-change recipe.
Using this information
This is a source-based reference record, not a recommendation to combine, stop or change medicines. A missing interaction record does not establish safe use. A qualified healthcare professional should consider the exact products, doses, other medicines and individual health circumstances.