Losec (Omeprazole) (Losec 20 mg) and Nilotinib: interaction and safety
This source-based reference is not a personal treatment recommendation. The relevance and management of an interaction depend on the exact products, route, dose and clinical situation.
Interaction mechanism
Proton pump inhibition can reduce absorption and exposure of Tasigna-type nilotinib capsules.
Clinical significance and safety
Losec 20 mg is a proton pump inhibitor. TASIGNA advises avoiding the combination because capsule exposure can decrease. A clinician may choose another approach with its own timing requirements; do not substitute a stomach medicine or transfer these instructions to another nilotinib formulation independently.
Using this information
This is a source-based reference record, not a recommendation to combine, stop or change medicines. A missing interaction record does not establish safe use. A qualified healthcare professional should consider the exact products, doses, other medicines and individual health circumstances.