Dronedarone (Multaq) (Dronedarone (Dronedaron)) and Midodrine (Midodrine (Midodrin)): interaction and safety
This source-based reference is not a personal treatment recommendation. The relevance and management of an interaction depend on the exact products, route, dose and clinical situation.
Interaction mechanism
Reflex pulse slowing with midodrine can add to other heart-rate-reducing effects.
Clinical significance and safety
Dronedarone (Multaq) and Midodrine: The midodrine information recommends monitoring with medicines that directly or indirectly reduce heart rate. A clinician should assess pulse and symptoms. Report marked dizziness, fainting or an unusually slow pulse promptly. This is a drug-class precaution, not a quantified study of the exact pair.
Using this information
This is a source-based reference record, not a recommendation to combine, stop or change medicines. A missing interaction record does not establish safe use. A qualified healthcare professional should consider the exact products, doses, other medicines and individual health circumstances.