Lustral (sertraline) (Lustral 50 mg) and Ziprasidone: interaction and safety
This source-based reference is not a personal treatment recommendation. The relevance and management of an interaction depend on the exact products, route, dose and clinical situation.
Interaction mechanism
Other serotonergic medicines can increase serotonin-syndrome risk during ziprasidone treatment.
Clinical significance and safety
Lustral (sertraline) and Ziprasidone: Other serotonergic medicines can increase serotonin-syndrome risk during ziprasidone treatment. Urgent assessment is needed for a new combination of agitation or confusion, fever, marked sweating, tremor or abnormal muscle movements. The warning does not provide a pair-specific incidence or establish that toxicity is inevitable.
Using this information
This is a source-based reference record, not a recommendation to combine, stop or change medicines. A missing interaction record does not establish safe use. A qualified healthcare professional should consider the exact products, doses, other medicines and individual health circumstances.