Ropinirole and Seroquel (quetiapine) (Seroquel 25 mg): interaction and safety
This source-based reference is not a personal treatment recommendation. The relevance and management of an interaction depend on the exact products, route, dose and clinical situation.
Interaction mechanism
Dopamine-blocking antipsychotics and metoclopramide can oppose ropinirole's therapeutic effect.
Clinical significance and safety
Ropinirole and Seroquel (quetiapine): Dopamine-blocking antipsychotics and metoclopramide can oppose ropinirole's therapeutic effect. A loss of Parkinson treatment benefit or worsening motor symptoms needs review by the treating team; neither treatment should be stopped abruptly to manage this interaction.
Using this information
This is a source-based reference record, not a recommendation to combine, stop or change medicines. A missing interaction record does not establish safe use. A qualified healthcare professional should consider the exact products, doses, other medicines and individual health circumstances.