Enzalutamide and Felodipine: interaction and safety
This source-based reference is not a personal treatment recommendation. The relevance and management of an interaction depend on the exact products, route, dose and clinical situation.
Interaction mechanism
Enzalutamide enzyme induction can reduce felodipine exposure.
Clinical significance and safety
With Enzalutamide and Felodipine, blood-pressure or angina control may worsen as felodipine exposure falls. Enzyme induction develops over time and can persist after enzalutamide is stopped. The clinician should monitor the medicine’s effect and manage any alternative or adjustment during both starting and stopping treatment. Do not try to compensate by increasing the dose yourself.
Using this information
This is a source-based reference record, not a recommendation to combine, stop or change medicines. A missing interaction record does not establish safe use. A qualified healthcare professional should consider the exact products, doses, other medicines and individual health circumstances.