Enzalutamide and Fesoterodine: interaction and safety
This source-based reference is not a personal treatment recommendation. The relevance and management of an interaction depend on the exact products, route, dose and clinical situation.
Interaction mechanism
CYP3A4 induction can markedly reduce exposure to the active fesoterodine metabolite.
Clinical significance and safety
Enzalutamide and Fesoterodine: The Toviaz SmPC does not recommend concurrent CYP3A4 inducers because treatment may become less effective. The clinician should review an alternative and symptom control. Do not increase fesoterodine yourself.
Using this information
This is a source-based reference record, not a recommendation to combine, stop or change medicines. A missing interaction record does not establish safe use. A qualified healthcare professional should consider the exact products, doses, other medicines and individual health circumstances.