Fesoterodine and Prozac (fluoxetine) (Prozac 20 mg): interaction and safety
This source-based reference is not a personal treatment recommendation. The relevance and management of an interaction depend on the exact products, route, dose and clinical situation.
Interaction mechanism
CYP2D6 inhibition may increase exposure to the active fesoterodine metabolite.
Clinical significance and safety
Fesoterodine and Prozac (fluoxetine): The prescriber should review tolerability and the full medicine list. Constipation, dry mouth and difficulty passing urine may increase. This interaction has not been clinically tested for every individual pair, so it is not a fixed dose-adjustment instruction. Report troublesome effects rather than changing treatment yourself.
Using this information
This is a source-based reference record, not a recommendation to combine, stop or change medicines. A missing interaction record does not establish safe use. A qualified healthcare professional should consider the exact products, doses, other medicines and individual health circumstances.