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Ortaakarsu · Medicine information Source-based drug interaction reference · English

Fosinopril and Olmesartan: interaction and safety

This source-based reference is not a personal treatment recommendation. The relevance and management of an interaction depend on the exact products, route, dose and clinical situation.

Interaction mechanism

Dual renin–angiotensin-system blockade increases hypotension, hyperkalaemia and renal risks.

Clinical significance and safety

Fosinopril and Olmesartan: Combining ACE inhibitors and ARBs, or two RAS-blocking treatments, is generally not recommended: most patients gain no extra benefit while adverse effects increase. If a specialist identifies a particular reason, blood pressure, kidney function and potassium require close monitoring. Do not start or alter such a combination yourself.

Using this information

This is a source-based reference record, not a recommendation to combine, stop or change medicines. A missing interaction record does not establish safe use. A qualified healthcare professional should consider the exact products, doses, other medicines and individual health circumstances.