Warfarin (Coumadin 5 mg) and Griseofulvin: interaction and safety
This source-based reference is not a personal treatment recommendation. The relevance and management of an interaction depend on the exact products, route, dose and clinical situation.
Interaction mechanism
Griseofulvin can reduce warfarin-type anticoagulant activity.
Clinical significance and safety
Warfarin (Coumadin 5 mg) and Griseofulvin: INR may need closer monitoring when griseofulvin starts and after it stops. The clinician should determine any adjustment. Report clotting or bleeding symptoms; do not increase warfarin yourself. This evidence concerns warfarin-type treatment, not automatically every anticoagulant.
Using this information
This is a source-based reference record, not a recommendation to combine, stop or change medicines. A missing interaction record does not establish safe use. A qualified healthcare professional should consider the exact products, doses, other medicines and individual health circumstances.