{"id":11679,"date":"2026-10-28T13:49:08","date_gmt":"2026-10-28T10:49:08","guid":{"rendered":"https:\/\/www.ortaakarsu.net\/?ism_drug=probenecid-probenesid"},"modified":"2026-10-28T13:49:09","modified_gmt":"2026-10-28T10:49:09","slug":"probenecid-probenesid","status":"publish","type":"ism_drug","link":"https:\/\/www.ortaakarsu.net\/?ism_drug=probenecid-probenesid","title":{"rendered":"Probenecid (Probenesid)"},"content":{"rendered":"<p><strong>Probenecid (Probenesid)<\/strong>, Probenesid etken maddesinin uluslararas\u0131 ad\u0131 \u00fczerinden haz\u0131rlanm\u0131\u015f bilgi sayfas\u0131d\u0131r.<\/p>\n<p><strong>Uygulama kapsam\u0131:<\/strong> A\u011f\u0131zdan. Yeterli s\u0131v\u0131 al\u0131m\u0131 ve gerekti\u011finde idrar pH y\u00f6netimi, b\u00f6brek ve kalp hastal\u0131klar\u0131 da dikkate al\u0131narak hekim taraf\u0131ndan planlan\u0131r; bu sayfa ki\u015fisel doz veya alkali tedavi plan\u0131 vermez. Farkl\u0131 g\u00fc\u00e7 ve farmas\u00f6tik formlar\u0131n birbirinin yerine kullan\u0131labilece\u011fi varsay\u0131lmamal\u0131d\u0131r.<\/p>\n<h2>T\u00fcrkiye\u2019de yurt d\u0131\u015f\u0131ndan temin kayd\u0131<\/h2>\n<p><a href=\"https:\/\/www.teb.org.tr\/docs\/3aac322e-7bec-4df1-a37f-0dd1757bed11\/yurtdisi-aktif-ilac-listesi\" rel=\"noopener\">TEB\u2019in 2 Ekim 2026 tarihli \u00fcr\u00fcn listesinde<\/a> bu etken maddeyi i\u00e7eren \u00fcr\u00fcn kay\u0131tlar\u0131 do\u011fruland\u0131: PROBENECID BIOKANOL 500 MG 100 TABLETTEN. <a href=\"https:\/\/www.titck.gov.tr\/dinamikmodul\/126\" rel=\"noopener\">T\u0130TCK\u2019nin 28 Eyl\u00fcl 2026 tarihli etken madde listesi<\/a> ayr\u0131ca kontrol edildi. Temin ko\u015fullar\u0131 hastaya, re\u00e7eteye, endikasyona ve gerekli onaylara g\u00f6re de\u011fi\u015febilir; listede yer almak g\u00fcncel stok veya geri \u00f6deme garantisi de\u011fildir. Klinik kullan\u0131m alan\u0131 a\u015fa\u011f\u0131daki \u00fcr\u00fcn belgesine g\u00f6re a\u00e7\u0131klan\u0131r; temin listesindeki tan\u0131 ko\u015fullar\u0131 tek ba\u015f\u0131na yeni bir klinik endikasyon olu\u015fturmaz.<\/p>\n<h2>Kaynaklar<\/h2>\n<ul>\n<li><a href=\"https:\/\/www.medsafe.govt.nz\/profs\/Datasheet\/a\/aft-Probenecidtab.pdf\" rel=\"noopener\">Medsafe Probenecid-AFT data sheet<\/a> (21.06.2024)<\/li>\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/4020675\/\" rel=\"noopener\">Probenecid impairment of acetaminophen and lorazepam clearance: direct inhibition of ether glucuronide formation<\/a> (Abernethy etal1985; PMID4020675)<\/li>\n<li><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=5d552de5-2d18-4464-bcaf-0311fa3f080d\" rel=\"noopener\">DailyMed Probenecid Marlex Pharmaceuticals<\/a> (18.11.2025)<\/li>\n<li><a href=\"https:\/\/www.medicines.org.uk\/emc\/product\/281\/smpc\" rel=\"noopener\">GSK Augmentin 625 mg SmPC; metin revizyonu 24.02.2026<\/a> (GSK Augmentin 625 mg SmPC; metin revizyonu 24.02.2026)<\/li>\n<li><a href=\"https:\/\/labeling.pfizer.com\/ShowLabeling.aspx?id=12271\" rel=\"noopener\">Pfizer Unasyn Oral sultamicillin SmPC; 28.10.2026 kontrol\u00fc<\/a> (Pfizer Unasyn Oral sultamicillin SmPC; 28.10.2026 kontrol\u00fc)<\/li>\n<li><a href=\"https:\/\/www.medicines.org.uk\/emc\/product\/426\/smpc\" rel=\"noopener\">Sandoz Cefuroxime 250 mg SmPC; metin revizyonu 25.03.2025<\/a> (Sandoz Cefuroxime 250 mg SmPC; metin revizyonu 25.03.2025)<\/li>\n<li><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/lookup.cfm?setid=8787ea15-bf90-4178-9b0f-08b075f1aa3d&amp;version=4\" rel=\"noopener\">DailyMed Cefdinir oral capsule; g\u00fcncelleme 24.03.2026<\/a> (DailyMed Cefdinir oral capsule; g\u00fcncelleme 24.03.2026)<\/li>\n<li><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/lookup.cfm?setid=1b53c6bb-0e8c-f49a-e063-6294a90a0f5a\" rel=\"noopener\">DailyMed Valacyclovir Viatris PI; 02\/2026<\/a> (DailyMed Valacyclovir Viatris PI; 02\/2026)<\/li>\n<li><a href=\"https:\/\/www.medicines.org.uk\/emc\/product\/7258\/smpc\" rel=\"noopener\">Milpharm Ciprofloxacin 750 mg SmPC; emc g\u00fcncellemesi 09.06.2026<\/a> (Milpharm Ciprofloxacin 750 mg SmPC; emc g\u00fcncellemesi 09.06.2026)<\/li>\n<li><a href=\"https:\/\/www.medicines.org.uk\/emc\/product\/1312\/smpc\" rel=\"noopener\">Aspen Zyloric SmPC; emc g\u00fcncellemesi 19.02.2025<\/a> (Aspen Zyloric SmPC; emc g\u00fcncellemesi 19.02.2025)<\/li>\n<li><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/lookup.cfm?setid=44f2f06d-7bc4-5239-e063-6394a90aac5e\" rel=\"noopener\">DailyMed Torsemide PI; 28.10.2026 kontrol\u00fc<\/a> (DailyMed Torsemide PI; 28.10.2026 kontrol\u00fc)<\/li>\n<li><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=32c4372e-54ea-4fc8-b9f8-827fa4c8edd3\" rel=\"noopener\">DailyMed Bumetanide tablets; metin g\u00fcncellemesi 24.11.2025<\/a> (DailyMed Bumetanide tablets; metin g\u00fcncellemesi 24.11.2025)<\/li>\n<li><a href=\"https:\/\/pdf.hres.ca\/dpd_pm\/00084141.PDF\" rel=\"noopener\">Knight Therapeutics Monurol Kanada \u00fcr\u00fcn monograf\u0131; 01.04.2026<\/a> (Knight Therapeutics Monurol Kanada \u00fcr\u00fcn monograf\u0131; 01.04.2026)<\/li>\n<li><a href=\"https:\/\/www.medicines.org.uk\/emc\/product\/13472\/smpc\" rel=\"noopener\">Milpharm Nitrofurantoin 50 mg SmPC; metin revizyonu 23.09.2026<\/a> (Milpharm Nitrofurantoin 50 mg SmPC; metin revizyonu 23.09.2026)<\/li>\n<li><a href=\"https:\/\/www.medicines.org.uk\/emc\/product\/12129\/smpc\" rel=\"noopener\">Ipca Furosemide 40 mg SmPC; emc g\u00fcncellemesi 15.07.2025<\/a> (Ipca Furosemide 40 mg SmPC; emc g\u00fcncellemesi 15.07.2025)<\/li>\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/466384\/\" rel=\"noopener\">Clinical pharmacological studies of amoxycillin: effect of probenecid<\/a> \u2014 Barbhaiya R; Thin RN; Turner P; Wadsworth J; British Journal of Venereal Diseases; 1979; DOI: 10.1136\/sti.55.3.211<\/li>\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/638616\/\" rel=\"noopener\">Prolongation and enhancement of serum methotrexate concentrations by probenecid<\/a> \u2014 Aherne GW; Piall E; Marks V; Mould G; White WF; British Medical Journal; 1978; DOI: 10.1136\/bmj.1.6120.1097<\/li>\n<\/ul>\n<p>Kaynak kontrol\u00fc: <time datetime=\"2026-10-28\">28 Ekim 2026<\/time>. Bu tarih, bir hekim veya eczac\u0131 taraf\u0131ndan klinik inceleme yap\u0131ld\u0131\u011f\u0131 anlam\u0131na gelmez. Ki\u015fisel tedavi plan\u0131 i\u00e7in kullan\u0131lan \u00fcr\u00fcn\u00fcn g\u00fcncel talimat\u0131 ve sa\u011fl\u0131k uzman\u0131n\u0131n de\u011ferlendirmesi esas al\u0131n\u0131r.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Probenecid (Probenesid), Probenesid etken maddesinin uluslararas\u0131 ad\u0131 \u00fczerinden haz\u0131rlanm\u0131\u015f bilgi  [&#8230;]<\/p>\n","protected":false},"featured_media":0,"template":"","ism_etken_madde":[1290],"class_list":["post-11679","ism_drug","type-ism_drug","status-publish","hentry","ism_etken_madde-probenesid"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=\/wp\/v2\/ism_drug\/11679","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=\/wp\/v2\/ism_drug"}],"about":[{"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=\/wp\/v2\/types\/ism_drug"}],"version-history":[{"count":1,"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=\/wp\/v2\/ism_drug\/11679\/revisions"}],"predecessor-version":[{"id":11680,"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=\/wp\/v2\/ism_drug\/11679\/revisions\/11680"}],"wp:attachment":[{"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=11679"}],"wp:term":[{"taxonomy":"ism_etken_madde","embeddable":true,"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=%2Fwp%2Fv2%2Fism_etken_madde&post=11679"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}