{"id":12316,"date":"2026-11-02T23:22:50","date_gmt":"2026-11-02T20:22:50","guid":{"rendered":"https:\/\/www.ortaakarsu.net\/?ism_drug=acalabrutinib"},"modified":"2026-11-02T23:22:50","modified_gmt":"2026-11-02T20:22:50","slug":"acalabrutinib","status":"publish","type":"ism_drug","link":"https:\/\/www.ortaakarsu.net\/?ism_drug=acalabrutinib","title":{"rendered":"Acalabrutinib"},"content":{"rendered":"<p>Akalabrutinib, belirli kan kanserlerinde kullan\u0131lan bir BTK inhibit\u00f6r\u00fcd\u00fcr. Sert kaps\u00fcl\u00fcn proton pompa inhibit\u00f6rleriyle emilim etkile\u015fimi, film kapl\u0131 tablet formuna otomatik olarak uygulanmamal\u0131d\u0131r.<\/p>\n<details>\n<summary>Kaynaklar ve belge kapsam\u0131<\/summary>\n<ul>\n<li><a href=\"https:\/\/www.ema.europa.eu\/en\/documents\/product-information\/calquence-epar-product-information_en.pdf\" rel=\"nofollow noopener\" target=\"_blank\">Calquence \u2014 EMA product information, Annex I SmPC<\/a><\/li>\n<li><a href=\"https:\/\/www.astrazeneca.com.tr\/content\/dam\/az-tr\/medicine\/PDF\/2025\/1311-kub-temiz-Calquence-kap.pdf\" rel=\"nofollow noopener\" target=\"_blank\">CALQUENCE 100 mg sert kaps\u00fcl K\u00dcB<\/a> \u2014 29.08.2022; K\u00dcB b\u00f6l\u00fcm 10<\/li>\n<li><a href=\"https:\/\/www.fda.gov\/drugs\/drug-interactions-labeling\/healthcare-professionals-fdas-examples-drugs-interact-cyp-enzymes-and-transporter-systems\" rel=\"nofollow noopener\" target=\"_blank\">FDA examples of drugs that interact with CYP enzymes and transporter systems<\/a><\/li>\n<li><a href=\"https:\/\/www.ema.europa.eu\/en\/documents\/product-information\/xtandi-epar-product-information_en.pdf\" rel=\"nofollow noopener\" target=\"_blank\">Xtandi \u2014 EMA product information, Annex I SmPC<\/a><\/li>\n<li><a href=\"https:\/\/www.ema.europa.eu\/en\/documents\/product-information\/erleada-epar-product-information_en.pdf\" rel=\"nofollow noopener\" target=\"_blank\">Erleada \u2014 EMA product information, Annex I SmPC<\/a><\/li>\n<li><a href=\"https:\/\/www.ema.europa.eu\/en\/documents\/product-information\/venclyxto-epar-product-information_en.pdf\" rel=\"nofollow noopener\" target=\"_blank\">Venclyxto \u2014 EMA product information, Annex I SmPC<\/a><\/li>\n<li><a href=\"https:\/\/www.ema.europa.eu\/en\/documents\/product-information\/kisqali-epar-product-information_en.pdf\" rel=\"nofollow noopener\" target=\"_blank\">Kisqali \u2014 EMA product information, Annex I SmPC<\/a><\/li>\n<\/ul>\n<\/details>\n","protected":false},"excerpt":{"rendered":"<p>Akalabrutinib, belirli kan kanserlerinde kullan\u0131lan bir BTK inhibit\u00f6r\u00fcd\u00fcr. Sert kaps\u00fcl\u00fcn  [&#8230;]<\/p>\n","protected":false},"featured_media":0,"template":"","ism_etken_madde":[1513],"class_list":["post-12316","ism_drug","type-ism_drug","status-publish","hentry","ism_etken_madde-akalabrutinib"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=\/wp\/v2\/ism_drug\/12316","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=\/wp\/v2\/ism_drug"}],"about":[{"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=\/wp\/v2\/types\/ism_drug"}],"version-history":[{"count":0,"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=\/wp\/v2\/ism_drug\/12316\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=12316"}],"wp:term":[{"taxonomy":"ism_etken_madde","embeddable":true,"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=%2Fwp%2Fv2%2Fism_etken_madde&post=12316"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}