{"id":12332,"date":"2026-11-02T23:22:51","date_gmt":"2026-11-02T20:22:51","guid":{"rendered":"https:\/\/www.ortaakarsu.net\/?ism_drug=bosentan"},"modified":"2026-11-02T23:22:51","modified_gmt":"2026-11-02T20:22:51","slug":"bosentan","status":"publish","type":"ism_drug","link":"https:\/\/www.ortaakarsu.net\/?ism_drug=bosentan","title":{"rendered":"Bosentan"},"content":{"rendered":"<p>Bosentan, pulmoner arteriyel hipertansiyonda kullan\u0131lan bir endotelin resept\u00f6r antagonistidir. Sistemik sklerozda yeni parmak \u00fclserlerinin azalt\u0131lmas\u0131nda da kullan\u0131labilir; d\u00fczenli karaci\u011fer ve kan say\u0131m\u0131 izlemi gerektirir.<\/p>\n<details>\n<summary>Kaynaklar ve belge kapsam\u0131<\/summary>\n<ul>\n<li><a href=\"https:\/\/www.ema.europa.eu\/en\/documents\/product-information\/tracleer-epar-product-information_en.pdf\" rel=\"nofollow noopener\" target=\"_blank\">Tracleer Summary of Product Characteristics<\/a><\/li>\n<li><a href=\"https:\/\/cdn.ilacrehberi.com\/tracleer-625-mg-film-tablet-a0f3-kub.pdf\" rel=\"nofollow noopener\" target=\"_blank\">TRACLEER 62,5 mg K\u0131sa \u00dcr\u00fcn Bilgisi<\/a><\/li>\n<li><a href=\"https:\/\/www.janssenlabels.com\/package-insert\/product-monograph\/prescribing-information\/TRACLEER-pi.pdf\" rel=\"nofollow noopener\" target=\"_blank\">Tracleer US Prescribing Information<\/a> \u2014 11\/2025<\/li>\n<li><a href=\"https:\/\/labeling.pfizer.com\/ShowLabeling.aspx?id=19599\" rel=\"nofollow noopener\" target=\"_blank\">Paxlovid US Prescribing Information<\/a><\/li>\n<li><a href=\"https:\/\/www.fda.gov\/drugs\/drug-interactions-labeling\/healthcare-professionals-fdas-examples-drugs-interact-cyp-enzymes-and-transporter-systems\" rel=\"nofollow noopener\" target=\"_blank\">FDA examples of drugs that interact with CYP enzymes and transporter systems<\/a><\/li>\n<\/ul>\n<\/details>\n","protected":false},"excerpt":{"rendered":"<p>Bosentan, pulmoner arteriyel hipertansiyonda kullan\u0131lan bir endotelin resept\u00f6r antagonistidir. Sistemik  [&#8230;]<\/p>\n","protected":false},"featured_media":0,"template":"","ism_etken_madde":[1521],"class_list":["post-12332","ism_drug","type-ism_drug","status-publish","hentry","ism_etken_madde-bosentan"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=\/wp\/v2\/ism_drug\/12332","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=\/wp\/v2\/ism_drug"}],"about":[{"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=\/wp\/v2\/types\/ism_drug"}],"version-history":[{"count":0,"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=\/wp\/v2\/ism_drug\/12332\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=12332"}],"wp:term":[{"taxonomy":"ism_etken_madde","embeddable":true,"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=%2Fwp%2Fv2%2Fism_etken_madde&post=12332"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}