{"id":12340,"date":"2026-11-02T23:22:52","date_gmt":"2026-11-02T20:22:52","guid":{"rendered":"https:\/\/www.ortaakarsu.net\/?ism_drug=darifenacin"},"modified":"2026-11-02T23:22:52","modified_gmt":"2026-11-02T20:22:52","slug":"darifenacin","status":"publish","type":"ism_drug","link":"https:\/\/www.ortaakarsu.net\/?ism_drug=darifenacin","title":{"rendered":"Darifenacin"},"content":{"rendered":"<p>Darifenasin, a\u015f\u0131r\u0131 aktif mesane yak\u0131nmalar\u0131n\u0131 azaltan bir antimuskarinik ila\u00e7t\u0131r. A\u011f\u0131z kurulu\u011fu ve kab\u0131zl\u0131k yapabilir; g\u00fc\u00e7l\u00fc CYP3A4 inhibit\u00f6rleriyle birlikte kullan\u0131m T\u00fcrk ve Birle\u015fik Krall\u0131k \u00fcr\u00fcn bilgilerinde kontrendikedir.<\/p>\n<details>\n<summary>Kaynaklar ve belge kapsam\u0131<\/summary>\n<ul>\n<li><a href=\"https:\/\/www.medicines.org.uk\/emc\/product\/15745\/smpc\" rel=\"nofollow noopener\" target=\"_blank\">Emselex 7.5 mg prolonged-release tablets: SmPC<\/a> \u2014 Text revised 2025-08-14<\/li>\n<li><a href=\"https:\/\/cdn.ilacrehberi.com\/emselex-75-mg-uzatilmis-salinimli-tablet-dc09-kub.pdf\" rel=\"nofollow noopener\" target=\"_blank\">EMSELEX 7.5 mg uzat\u0131lm\u0131\u015f sal\u0131ml\u0131 tablet K\u0131sa \u00dcr\u00fcn Bilgisi<\/a><\/li>\n<li><a href=\"https:\/\/www.fda.gov\/drugs\/drug-interactions-labeling\/healthcare-professionals-fdas-examples-drugs-interact-cyp-enzymes-and-transporter-systems\" rel=\"nofollow noopener\" target=\"_blank\">FDA examples of drugs that interact with CYP enzymes and transporter systems<\/a><\/li>\n<li><a href=\"https:\/\/www.ema.europa.eu\/en\/documents\/product-information\/xtandi-epar-product-information_en.pdf\" rel=\"nofollow noopener\" target=\"_blank\">Xtandi (enzalutamide): EMA product information<\/a><\/li>\n<li><a href=\"https:\/\/www.ema.europa.eu\/en\/documents\/product-information\/erleada-epar-product-information_en.pdf\" rel=\"nofollow noopener\" target=\"_blank\">Erleada (apalutamide): EMA product information<\/a><\/li>\n<\/ul>\n<\/details>\n","protected":false},"excerpt":{"rendered":"<p>Darifenasin, a\u015f\u0131r\u0131 aktif mesane yak\u0131nmalar\u0131n\u0131 azaltan bir antimuskarinik ila\u00e7t\u0131r. A\u011f\u0131z  [&#8230;]<\/p>\n","protected":false},"featured_media":0,"template":"","ism_etken_madde":[1525],"class_list":["post-12340","ism_drug","type-ism_drug","status-publish","hentry","ism_etken_madde-darifenasin"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=\/wp\/v2\/ism_drug\/12340","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=\/wp\/v2\/ism_drug"}],"about":[{"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=\/wp\/v2\/types\/ism_drug"}],"version-history":[{"count":0,"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=\/wp\/v2\/ism_drug\/12340\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=12340"}],"wp:term":[{"taxonomy":"ism_etken_madde","embeddable":true,"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=%2Fwp%2Fv2%2Fism_etken_madde&post=12340"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}