{"id":12342,"date":"2026-11-02T23:22:52","date_gmt":"2026-11-02T20:22:52","guid":{"rendered":"https:\/\/www.ortaakarsu.net\/?ism_drug=darolutamide"},"modified":"2026-11-02T23:22:52","modified_gmt":"2026-11-02T20:22:52","slug":"darolutamide","status":"publish","type":"ism_drug","link":"https:\/\/www.ortaakarsu.net\/?ism_drug=darolutamide","title":{"rendered":"Darolutamide"},"content":{"rendered":"<p>Darolutamid, belirli prostat kanseri t\u00fcrlerinde kullan\u0131lan bir androjen resept\u00f6r inhibit\u00f6r\u00fcd\u00fcr. Enzalutamid ve apalutamidin g\u00fc\u00e7l\u00fc CYP ind\u00fcksiyonu ile ayn\u0131 etkile\u015fim profiline sahip de\u011fildir; \u00f6zellikle rosuvastatin ve ta\u015f\u0131y\u0131c\u0131 etkile\u015fimleri \u00f6nemlidir.<\/p>\n<details>\n<summary>Kaynaklar ve belge kapsam\u0131<\/summary>\n<ul>\n<li><a href=\"https:\/\/www.ema.europa.eu\/en\/documents\/product-information\/nubeqa-epar-product-information_en.pdf\" rel=\"nofollow noopener\" target=\"_blank\">Nubeqa \u2014 EMA product information, Annex I SmPC<\/a><\/li>\n<li><a href=\"https:\/\/prospektus.co\/api-proxy\/drugs\/nubeqa-300-mg-film-kapli-tablet\/kub\/pdf\" rel=\"nofollow noopener\" target=\"_blank\">NUBEQA 300 mg film kapl\u0131 tablet K\u00dcB<\/a><\/li>\n<li><a href=\"https:\/\/www.ema.europa.eu\/en\/documents\/product-information\/xtandi-epar-product-information_en.pdf\" rel=\"nofollow noopener\" target=\"_blank\">Xtandi \u2014 EMA product information, Annex I SmPC<\/a><\/li>\n<li><a href=\"https:\/\/www.ema.europa.eu\/en\/documents\/product-information\/erleada-epar-product-information_en.pdf\" rel=\"nofollow noopener\" target=\"_blank\">Erleada \u2014 EMA product information, Annex I SmPC<\/a><\/li>\n<li><a href=\"https:\/\/www.fda.gov\/drugs\/drug-interactions-labeling\/healthcare-professionals-fdas-examples-drugs-interact-cyp-enzymes-and-transporter-systems\" rel=\"nofollow noopener\" target=\"_blank\">FDA examples of drugs that interact with CYP enzymes and transporter systems<\/a><\/li>\n<\/ul>\n<\/details>\n","protected":false},"excerpt":{"rendered":"<p>Darolutamid, belirli prostat kanseri t\u00fcrlerinde kullan\u0131lan bir androjen resept\u00f6r inhibit\u00f6r\u00fcd\u00fcr.  [&#8230;]<\/p>\n","protected":false},"featured_media":0,"template":"","ism_etken_madde":[1526],"class_list":["post-12342","ism_drug","type-ism_drug","status-publish","hentry","ism_etken_madde-darolutamid"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=\/wp\/v2\/ism_drug\/12342","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=\/wp\/v2\/ism_drug"}],"about":[{"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=\/wp\/v2\/types\/ism_drug"}],"version-history":[{"count":0,"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=\/wp\/v2\/ism_drug\/12342\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=12342"}],"wp:term":[{"taxonomy":"ism_etken_madde","embeddable":true,"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=%2Fwp%2Fv2%2Fism_etken_madde&post=12342"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}