{"id":12406,"date":"2026-11-02T23:22:58","date_gmt":"2026-11-02T20:22:58","guid":{"rendered":"https:\/\/www.ortaakarsu.net\/?ism_drug=riociguat"},"modified":"2026-11-02T23:22:58","modified_gmt":"2026-11-02T20:22:58","slug":"riociguat","status":"publish","type":"ism_drug","link":"https:\/\/www.ortaakarsu.net\/?ism_drug=riociguat","title":{"rendered":"Riociguat"},"content":{"rendered":"<p>Riociguat, se\u00e7ilmi\u015f PAH ve ameliyat edilemeyen ya da cerrahi sonras\u0131 s\u00fcren\/tekrarlayan kronik tromboembolik pulmoner hipertansiyonda kullan\u0131lan \u00e7\u00f6z\u00fcn\u00fcr guanilat siklaz uyar\u0131c\u0131s\u0131d\u0131r. Nitratlar ve PDE5 inhibit\u00f6rleriyle birlikte al\u0131nmaz.<\/p>\n<details>\n<summary>Kaynaklar ve belge kapsam\u0131<\/summary>\n<ul>\n<li><a href=\"https:\/\/www.ema.europa.eu\/en\/documents\/product-information\/adempas-epar-product-information_en.pdf\" rel=\"nofollow noopener\" target=\"_blank\">Adempas Summary of Product Characteristics<\/a><\/li>\n<li><a href=\"https:\/\/www.ilacdata.com\/kub\/289.pdf\" rel=\"nofollow noopener\" target=\"_blank\">ADEMPAS 1 mg K\u0131sa \u00dcr\u00fcn Bilgisi<\/a><\/li>\n<li><a href=\"https:\/\/www.medicines.org.uk\/emc\/product\/5334\/smpc\" rel=\"nofollow noopener\" target=\"_blank\">Adempas Summary of Product Characteristics<\/a><\/li>\n<li><a href=\"https:\/\/www.fda.gov\/drugs\/drug-interactions-labeling\/healthcare-professionals-fdas-examples-drugs-interact-cyp-enzymes-and-transporter-systems\" rel=\"nofollow noopener\" target=\"_blank\">FDA examples of drugs that interact with CYP enzymes and transporter systems<\/a><\/li>\n<li><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=fa7d93e3-b69b-4e02-8146-89760cd8e9d6\" rel=\"nofollow noopener\" target=\"_blank\">Stendra (avanafil) US Prescribing Information<\/a> \u2014 PI revised 10\/2022; DailyMed posting 18\/07\/2024<\/li>\n<li><a href=\"https:\/\/www.ema.europa.eu\/en\/documents\/product-information\/verquvo-epar-product-information_en.pdf\" rel=\"nofollow noopener\" target=\"_blank\">Verquvo Summary of Product Characteristics<\/a><\/li>\n<li><a href=\"https:\/\/www.prospektus.co\/ilaclar\/verquvo-10-mg-film-kapli-tablet\/kisa-urun-bilgisi\" rel=\"nofollow noopener\" target=\"_blank\">VERQUVO 10 mg K\u0131sa \u00dcr\u00fcn Bilgisi<\/a><\/li>\n<\/ul>\n<\/details>\n","protected":false},"excerpt":{"rendered":"<p>Riociguat, se\u00e7ilmi\u015f PAH ve ameliyat edilemeyen ya da cerrahi sonras\u0131  [&#8230;]<\/p>\n","protected":false},"featured_media":0,"template":"","ism_etken_madde":[1558],"class_list":["post-12406","ism_drug","type-ism_drug","status-publish","hentry","ism_etken_madde-riociguat"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=\/wp\/v2\/ism_drug\/12406","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=\/wp\/v2\/ism_drug"}],"about":[{"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=\/wp\/v2\/types\/ism_drug"}],"version-history":[{"count":0,"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=\/wp\/v2\/ism_drug\/12406\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=12406"}],"wp:term":[{"taxonomy":"ism_etken_madde","embeddable":true,"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=%2Fwp%2Fv2%2Fism_etken_madde&post=12406"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}