{"id":16035,"date":"2026-11-04T18:10:42","date_gmt":"2026-11-04T15:10:42","guid":{"rendered":"https:\/\/www.ortaakarsu.net\/?page_id=16035"},"modified":"2026-11-04T18:10:42","modified_gmt":"2026-11-04T15:10:42","slug":"english-interaction-imatinib-oxcarbazepine-okskarbazepin","status":"publish","type":"page","link":"https:\/\/www.ortaakarsu.net\/?page_id=16035","title":{"rendered":"Imatinib and Oxcarbazepine (Oxcarbazepine (Okskarbazepin)): interaction and safety"},"content":{"rendered":"<h2>Interaction mechanism<\/h2>\n<p>Enzyme induction by oxcarbazepine can lower imatinib exposure.<\/p>\n<h2>Clinical significance and safety<\/h2>\n<p>Oxcarbazepine is included among enzyme-inducing antiepileptic drugs in the GLEEVEC clinical interaction data. Lower imatinib exposure can compromise treatment, so oncology and neurology teams should coordinate the regimen. Do not interrupt an antiseizure medicine independently.<\/p>\n<h2>Using this information<\/h2>\n<p>This is a source-based reference record, not a recommendation to combine, stop or change medicines. A missing interaction record does not establish safe use. A qualified healthcare professional should consider the exact products, doses, other medicines and individual health circumstances.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Oxcarbazepine is included among enzyme-inducing antiepileptic drugs in the GLEEVEC clinical interaction data. Lower imatinib exposure can compromise treatment, so oncology and\u2026<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-16035","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=\/wp\/v2\/pages\/16035","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=16035"}],"version-history":[{"count":0,"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=\/wp\/v2\/pages\/16035\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=16035"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}