{"id":17692,"date":"2026-11-04T18:12:43","date_gmt":"2026-11-04T15:12:43","guid":{"rendered":"https:\/\/www.ortaakarsu.net\/?page_id=17692"},"modified":"2026-11-04T18:12:43","modified_gmt":"2026-11-04T15:12:43","slug":"english-interaction-aldactone-25-mg-treprostinil","status":"publish","type":"page","link":"https:\/\/www.ortaakarsu.net\/?page_id=17692","title":{"rendered":"Aldactone (Spironolactone) (Aldactone 25 mg) and Treprostinil: interaction and safety"},"content":{"rendered":"<h2>Interaction mechanism<\/h2>\n<p>Diuretic-related volume reduction and treprostinil vasodilation can increase blood-pressure lowering.<\/p>\n<h2>Clinical significance and safety<\/h2>\n<p>Aldactone (Spironolactone) and Treprostinil: Treprostinil and diuretics may be deliberately combined in specialist treatment. Blood pressure, fluid status and dizziness or fainting should be monitored. Do not change fluid intake or infusion or diuretic doses yourself; the specialist should determine the plan.<\/p>\n<h2>Using this information<\/h2>\n<p>This is a source-based reference record, not a recommendation to combine, stop or change medicines. A missing interaction record does not establish safe use. A qualified healthcare professional should consider the exact products, doses, other medicines and individual health circumstances.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Aldactone (Spironolactone) and Treprostinil: Treprostinil and diuretics may be deliberately combined in specialist treatment. Blood pressure, fluid status and dizziness or fai\u2026<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-17692","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=\/wp\/v2\/pages\/17692","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=17692"}],"version-history":[{"count":0,"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=\/wp\/v2\/pages\/17692\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=17692"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}