{"id":7768,"date":"2022-01-01T22:01:33","date_gmt":"2022-01-01T19:01:33","guid":{"rendered":"https:\/\/www.ortaakarsu.net\/?p=7768"},"modified":"2025-05-01T15:37:52","modified_gmt":"2025-05-01T12:37:52","slug":"olanzapin-yan-etkileri-ve-kullanici-yorumlari","status":"publish","type":"post","link":"https:\/\/www.ortaakarsu.net\/?p=7768","title":{"rendered":"Olanzapin Yan Etkileri ve Kullan\u0131c\u0131 Yorumlar\u0131"},"content":{"rendered":"\r\n

Olanzapin yan etkileri<\/strong> konusunda bilgi vermeden yap\u0131lan akademik \u00e7al\u0131\u015fmalarla Olanzapin’in etki mekanizmas\u0131n\u0131 ve klinik \u00e7al\u0131\u015fmalar\u0131n mant\u0131\u011f\u0131n\u0131 anlamaya \u00e7al\u0131\u015fal\u0131m.<\/p>\r\n\r\n\r\n\r\n

Olanzapin (Nedir ve Ne \u0130\u015fe Yarar?)<\/h3>\r\n

Olanzapin, \u015fizofreni tedavisinde kullan\u0131lan \u201catipik\u201d (yeni nesil) bir antipsikotiktir. Hem \u201cpozitif\u201d semptomlar\u0131<\/strong> (\u00f6rne\u011fin sanr\u0131lar, hal\u00fcsinasyonlar) hem de \u201cnegatif\u201d semptomlar\u0131<\/strong> (\u00f6rne\u011fin i\u00e7e kapanma, duygusal donukluk) hafifletir. \u00c7ok merkezli klinik \u00e7al\u0131\u015fmalar, ilac\u0131n bu iki semptom grubunda da etkili oldu\u011funu g\u00f6stermi\u015ftir.<\/p>\r\n

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Ba\u015fl\u0131ca Avantajlar\u0131<\/h3>\r\n
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Avantaj<\/th>\r\nNe Anlama Gelir?<\/th>\r\nHastaya Faydas\u0131<\/th>\r\n<\/tr>\r\n<\/thead>\r\n
Daha az ekstrapiramidal belirti<\/strong><\/td>\r\nKas sertli\u011fi, titreme gibi klasik ila\u00e7lar\u0131n s\u0131k g\u00f6r\u00fclen motor yan etkileri azal\u0131r<\/td>\r\nG\u00fcnl\u00fck ya\u015famda daha az hareket k\u0131s\u0131tl\u0131l\u0131\u011f\u0131<\/td>\r\n<\/tr>\r\n
Prolaktin d\u00fczeyini \u00e7ok az y\u00fckseltir<\/strong><\/td>\r\nHormonal dengesizlik (\u00f6r. adet d\u00fczensizli\u011fi, s\u00fct gelmesi) riski d\u00fc\u015fer<\/td>\r\nDaha iyi hormonal tolerans<\/td>\r\n<\/tr>\r\n
Genellikle iyi tolere edilir<\/strong><\/td>\r\nYan etkilerin \u00e7o\u011fu hafif veya orta d\u00fczeydedir<\/td>\r\nTedaviye uyum artar<\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>\r\n
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\u00a0<\/div>\r\n<\/div>\r\n<\/div>\r\n<\/div>\r\n
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V\u00fccutta Nas\u0131l Davran\u0131r? (Farmakokinetik)<\/h3>\r\n
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\u00d6zellik<\/th>\r\nA\u00e7\u0131klamas\u0131<\/th>\r\nKolay Anlat\u0131m<\/th>\r\n<\/tr>\r\n<\/thead>\r\n
Yar\u0131 \u00f6m\u00fcr<\/strong><\/td>\r\n\u0130lac\u0131n kandaki miktar\u0131n\u0131n yar\u0131ya inme s\u00fcresi: ortalama \u2248 33 saat<\/strong> (21-54 saat)<\/td>\r\nTek doz al\u0131nd\u0131ktan sonra ilac\u0131n bedenden tamamen temizlenmesi \u2248 1 hafta s\u00fcrer<\/td>\r\n<\/tr>\r\n
Klerens<\/strong><\/td>\r\nKaraci\u011ferin ilac\u0131 kandaki plazmadan temizleme h\u0131z\u0131; ortalama 26 L\/saat<\/strong><\/td>\r\n\u201cBedenin s\u00fcp\u00fcrme h\u0131z\u0131\u201d<\/td>\r\n<\/tr>\r\n
At\u0131l\u0131m<\/strong><\/td>\r\n\u0130lac\u0131n %60\u2019\u0131 idrarla<\/strong>, %30\u2019u d\u0131\u015fk\u0131yla<\/strong> at\u0131l\u0131r<\/td>\r\nB\u00f6brek ve ba\u011f\u0131rsaklar yoluyla v\u00fccuttan uzakla\u015f\u0131r<\/td>\r\n<\/tr>\r\n
Protein ba\u011flanmas\u0131<\/strong><\/td>\r\nKandaki alb\u00fcmine %90, \u03b1\u2081-asit glikoproteine %77 oran\u0131nda ba\u011flan\u0131r<\/td>\r\nBa\u011fl\u0131 k\u0131s\u0131m etkisiz, serbest k\u0131s\u0131m etkilidir<\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>\r\n
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\u00a0<\/div>\r\n<\/div>\r\n<\/div>\r\n<\/div>\r\n
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Kimlerde Farkl\u0131 \u00c7al\u0131\u015f\u0131r?<\/h3>\r\n