{"id":8040,"date":"2022-08-21T13:52:50","date_gmt":"2022-08-21T10:52:50","guid":{"rendered":"https:\/\/www.ortaakarsu.net\/?p=8040"},"modified":"2025-04-28T15:55:51","modified_gmt":"2025-04-28T12:55:51","slug":"buscopan-ampul-ne-ise-yarar","status":"publish","type":"post","link":"https:\/\/www.ortaakarsu.net\/?p=8040","title":{"rendered":"Buscopan Ampul Ne \u0130\u015fe Yarar?"},"content":{"rendered":"\r\n

Buscopan ampul ne i\u015fe yarar<\/strong> sorusuna verilecek en k\u0131sa yan\u0131t ani ve \u015fiddetli kas\u0131lmalar\u0131n h\u0131zl\u0131 bir \u015fekilde giderilmesini sa\u011flad\u0131\u011f\u0131 \u015feklindedir. Buscopan ampul, yani enjeksiyonluk olarak sat\u0131ld\u0131\u011f\u0131 gibi tablet yani oral kullan\u0131m i\u00e7in de \u00e7e\u015fitli formlarda bulunmaktad\u0131r. Buscopan ampul 20 mg\/ml<\/strong> \u015feklindeki dozlarda sat\u0131lmaktad\u0131r. Bu ila\u00e7 hiyosin-N-butilbrom\u00fcr etken maddesini i\u00e7ermektedir.<\/strong> Bu etken maddenin farkl\u0131 kullan\u0131m alanlar\u0131na bakal\u0131m:<\/p>\r\n\r\n\r\n

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\"Buscopan\r\n
Buscopan Ampul Ne \u0130\u015fe Yarar ve etken madde nedir?<\/figcaption>\r\n<\/figure>\r\n<\/div>\r\n\r\n\r\n

Buscopan Amp<\/strong>ul Ne \u0130\u015fe Yarar<\/strong>; Kar\u0131n Kramlar\u0131<\/h2>\r\n\r\n\r\n\r\n

Buscopan ampul ne i\u015fe yarar<\/strong> sorusuna verilecek en yayg\u0131n cevap kar\u0131n kramplar\u0131 i\u00e7in kullan\u0131lmas\u0131d\u0131r. Kar\u0131n kramplar\u0131 ve a\u011fr\u0131, tahmini prevalans\u0131 \u2264%30 olan Bat\u0131 \u00fclkelerinin yeti\u015fkin n\u00fcfusunda s\u0131k g\u00f6r\u00fclen bir sorundur. Hyoscine butylbromide (scopolamine butylbromide) [Buscopan\u00ae\/Buscapina\u00ae], gastrointestinal (GI) spazmlar\u0131n neden oldu\u011fu kramplarla ili\u015fkili kar\u0131n a\u011fr\u0131s\u0131n\u0131n tedavisi i\u00e7in belirtilen spazm \u00f6nleyici bir ila\u00e7t\u0131r<\/strong>. \u0130lk olarak 1951’de Almanya’da tescil edildi ve 1952’de pazarland\u0131 ve o zamandan beri hem re\u00e7eteli ila\u00e7 hem de bir\u00e7ok \u00fclkede re\u00e7etesiz sat\u0131lan bir ila\u00e7 olarak d\u00fcnya \u00e7ap\u0131nda kullan\u0131labilir hale geldi.<\/p>\r\n\r\n\r\n\r\n

Farmakolojik \u00e7al\u0131\u015fmalar, hiposin butilbrom\u00fcr\u00fcn, GI yolunun d\u00fcz kas h\u00fccrelerinde bulunan muskarinik resept\u00f6rlere y\u00fcksek afinitesi olan antikolinerjik bir ila\u00e7 oldu\u011funu ortaya koymu\u015ftur. Antikolinerjik etkisi, d\u00fcz kas gev\u015fetici\/spazmolitik etki g\u00f6sterir. Mide-ba\u011f\u0131rsak yolundaki muskarinik resept\u00f6rlerin blokaj\u0131, krampa ba\u011fl\u0131 kar\u0131n a\u011fr\u0131s\u0131n\u0131n tedavisinde kullan\u0131m\u0131n\u0131n temelidir. Hyoscine butylbromide ayr\u0131ca ganglion bloke edici bir etki yaratan nikotinik resept\u00f6rlere de ba\u011flan\u0131r.<\/p>\r\n\r\n\r\n\r\n

\u0130nsanlarda yap\u0131lan birka\u00e7 farmakokinetik \u00e7al\u0131\u015fma, oral uygulamadan sonra hiposin butilbrom\u00fcr\u00fcn d\u00fc\u015f\u00fck sistemik kullan\u0131labilirli\u011fini tutarl\u0131 bir \u015fekilde g\u00f6stermi\u015ftir ve ilac\u0131n plazma konsantrasyonlar\u0131 genellikle kantitasyon s\u0131n\u0131r\u0131n\u0131n alt\u0131ndad\u0131r. B\u00f6brek at\u0131l\u0131m\u0131ndan tahmin edilen hiposin butilbrom\u00fcr\u00fcn biyoyararlan\u0131m\u0131 genellikle <%1 olmu\u015ftur. Bununla birlikte, muskarinik resept\u00f6rler i\u00e7in y\u00fcksek doku afinitesi nedeniyle, hiyosin b\u00fctilbrom\u00fcr, ba\u011f\u0131rsakta etki b\u00f6lgesinde mevcut kal\u0131r ve lokal bir spazmolitik etki uygular. Bu da Buscopan ampul ne i\u015fe yarar<\/strong> sorusuna verilebilecek en net cevab\u0131 olu\u015fturur.<\/p>\r\n\r\n\r\n\r\n

Kaynak: https:\/\/doi.org\/10.2165\/00003495-200767090-00007<\/a><\/p>\r\n\r\n\r\n\r\n

Do\u011fum s\u00fcresinin k\u0131salt\u0131lmas\u0131<\/h2>\r\n\r\n\r\n\r\n

Buscopan ampul ne i\u015fe yarar<\/strong> sorusuna verilebilecek di\u011fer bir cevap do\u011fum s\u0131ras\u0131nda kas\u0131lmalar\u0131n kontrol\u00fcd\u00fcr. Maternal veya fetal sonu\u00e7lar\u0131 tehlikeye atmadan do\u011fumu art\u0131rma ve s\u00fcresini k\u0131saltma giri\u015fimleri hem hastalar hem de do\u011fum uzmanlar\u0131 i\u00e7in faydal\u0131d\u0131r. Do\u011fumun s\u00fcresini belirleyen iki ana fakt\u00f6r, uterus kontraktilitesi ve servikal geni\u015fleme h\u0131z\u0131d\u0131r.<\/p>\r\n\r\n\r\n\r\n

Membranlar\u0131 s\u00fcp\u00fcrme, servikal germe ve amniyotomi gibi mekanik fakt\u00f6rlere ek olarak, \u00e7e\u015fitli farmakolojik ajanlar\u0131n servikal dilatasyonu kolayla\u015ft\u0131rd\u0131\u011f\u0131 bulunmu\u015ftur. Oksitosinin rol\u00fc, eme\u011fin g\u00fc\u00e7lendirilmesinde d\u00fcnya \u00e7ap\u0131nda kurulmu\u015ftur ve hiyal\u00fcronidaz\u0131n servikal uygulamas\u0131 da bir miktar ba\u015far\u0131yla kullan\u0131lm\u0131\u015ft\u0131r. Phloroglucinol, plasebo gruplar\u0131yla kar\u015f\u0131la\u015ft\u0131r\u0131ld\u0131\u011f\u0131nda, ilk a\u015famada do\u011fum eylemi s\u00fcresinde ortalama %34 ve ikinci a\u015famada ortalama %23 azalma ile sonu\u00e7lar\u0131 elde edilmi\u015ftir. Valehamat brom\u00fcr n\u00f6rotropik ve muskulotropik etkilere sahiptir ve serviks kaslar\u0131n\u0131n gev\u015femesine neden olarak serviksin h\u0131zl\u0131 geni\u015flemesine ve do\u011fum s\u00fcresinin k\u0131salmas\u0131na neden olur.<\/p>\r\n\r\n\r\n\r\n

On plasebo kontroll\u00fc \u00e7al\u0131\u015fma, oral veya rektal hiposin butilbrom\u00fcr\u00fcn etkinli\u011fini ve g\u00fcvenli\u011fini de\u011ferlendirmi\u015ftir. Hyoscine butylbromide, kramplar\u0131n neden oldu\u011fu kar\u0131n a\u011fr\u0131s\u0131n\u0131n tedavisinde kullan\u0131m\u0131n\u0131 destekleyen t\u00fcm bu denemelerde faydal\u0131 olarak kabul edildi. Hyoscine butylbromide kanda zar zor emilir ve saptanabilir ve kan-beyin bariyerini ge\u00e7mez ve bu nedenle genellikle iyi tolere edilir. Birka\u00e7 advers olay bildirilmi\u015ftir; \u00f6zellikle antikolinerjiklerle ili\u015fkili yan etkilerin insidans\u0131nda \u00f6nemli bir art\u0131\u015f g\u00f6zlenmemi\u015ftir<\/p>\r\n\r\n\r\n\r\n

Kaynak: https:\/\/doi.org\/10.1016\/j.ijgo.2007.08.020<\/a><\/p>\r\n\r\n\r\n\r\n

Ba\u015fka bir a\u011fr\u0131 kesici olan Flextra 400 mg Nedir? Ne \u0130\u00e7in Kullan\u0131l\u0131r? Yan Etkileri Nelerdir?<\/a> yaz\u0131nda farkl\u0131 kullan\u0131m ama\u00e7lar\u0131na g\u00f6re bilgiler bulunmaktad\u0131r.<\/p>\r\n\r\n\r\n\r\n

 <\/p>\r\n","protected":false},"excerpt":{"rendered":"

Buscopan ampul ne i\u015fe yarar sorusuna verilecek en k\u0131sa yan\u0131t […]<\/p>\n","protected":false},"author":1,"featured_media":9535,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[122],"tags":[337,110,340,104,92,125,143,106,9,339,341],"class_list":["post-8040","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-molekul","tag-agri-kesici","tag-biyokimya","tag-buscopan","tag-enzim-inhibisyonu","tag-enzimler","tag-ilac","tag-ilac-gelistirme","tag-ilac-kesfi","tag-ilac-tasarimi","tag-kramp","tag-spazm"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=\/wp\/v2\/posts\/8040","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=8040"}],"version-history":[{"count":3,"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=\/wp\/v2\/posts\/8040\/revisions"}],"predecessor-version":[{"id":9536,"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=\/wp\/v2\/posts\/8040\/revisions\/9536"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=\/wp\/v2\/media\/9535"}],"wp:attachment":[{"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=8040"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=8040"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.ortaakarsu.net\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=8040"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}