Raltegravir and Carbamazepine (Tegretol CR 400 mg): interaction and safety
This source-based reference is not a personal treatment recommendation. The relevance and management of an interaction depend on the exact products, route, dose and clinical situation.
Interaction mechanism
Strong enzyme induction may reduce raltegravir exposure; the magnitude is uncertain.
Clinical significance and safety
The label does not recommend raltegravir with carbamazepine or phenytoin because the effects of these strong inducers are uncertain. The HIV and seizure-treatment teams should assess the combination before either treatment changes.
Using this information
This is a source-based reference record, not a recommendation to combine, stop or change medicines. A missing interaction record does not establish safe use. A qualified healthcare professional should consider the exact products, doses, other medicines and individual health circumstances.