Avanafil and Diflucan 150 mg (Fluconazole): interaction and safety
This source-based reference is not a personal treatment recommendation. The relevance and management of an interaction depend on the exact products, route, dose and clinical situation.
Interaction mechanism
Moderate CYP3A4 inhibition can increase avanafil exposure.
Clinical significance and safety
Avanafil and Diflucan 150 mg (Fluconazole): The prescriber should review the avanafil regimen and the lower prescribing limits required with moderate inhibitors. Do not increase the dose yourself. Marked dizziness or fainting needs assessment. Moderate inhibition is distinct from the prohibition applying to strong inhibitors.
Using this information
This is a source-based reference record, not a recommendation to combine, stop or change medicines. A missing interaction record does not establish safe use. A qualified healthcare professional should consider the exact products, doses, other medicines and individual health circumstances.