Diflucan 150 mg (Fluconazole) and Silodosin: interaction and safety
This source-based reference is not a personal treatment recommendation. The relevance and management of an interaction depend on the exact products, route, dose and clinical situation.
Interaction mechanism
Moderate CYP3A4 inhibition may reduce silodosin metabolism and increase exposure.
Clinical significance and safety
Diflucan 150 mg (Fluconazole) and Silodosin: The prescriber should review concurrent treatment and monitor dizziness or low blood pressure. The source distinguishes moderate inhibition from the contraindication with strong CYP3A4 inhibitors. Do not discontinue or adjust the medicines yourself; promptly report severe dizziness or fainting.
Using this information
This is a source-based reference record, not a recommendation to combine, stop or change medicines. A missing interaction record does not establish safe use. A qualified healthcare professional should consider the exact products, doses, other medicines and individual health circumstances.